Advancements in MRI-Based Methods for Targeting Transcranial Focused Ultrasound

The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for transcranial MR-guided focused ultrasound (MRgFUS). Transcranial MRgFUS is a mature technology with a number of neurological applications [1]. For e...

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Main Author: Jonathan, Sumeeth Vijay
Format: Dissertation
Language:English
Published: ProQuest Dissertations & Theses 01-01-2020
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Abstract The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for transcranial MR-guided focused ultrasound (MRgFUS). Transcranial MRgFUS is a mature technology with a number of neurological applications [1]. For example, non-invasive ablative thalamotomy is an FDA-approved treatment option for patients with essential tremor [2] or tremor-dominant Parkinsonism [3]. Recent human trials have been successful for blood-brain barrier (BBB) opening [4] and neuromodulation [5–8] via low intensity FUS.
AbstractList The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for transcranial MR-guided focused ultrasound (MRgFUS). Transcranial MRgFUS is a mature technology with a number of neurological applications [1]. For example, non-invasive ablative thalamotomy is an FDA-approved treatment option for patients with essential tremor [2] or tremor-dominant Parkinsonism [3]. Recent human trials have been successful for blood-brain barrier (BBB) opening [4] and neuromodulation [5–8] via low intensity FUS.
Author Jonathan, Sumeeth Vijay
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Snippet The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for...
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SubjectTerms Biomedical engineering
Brain
Grammatical case
Health care management
Magnetic resonance imaging
Medical imaging
Neurosciences
Patients
Public health
Title Advancements in MRI-Based Methods for Targeting Transcranial Focused Ultrasound
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