Characterizing Mechanisms of Regulatory Specificity in the Nuclear Receptors and General Transcriptional Cofactors

Gene regulation, at its most basic level, is controlled by transcription factors (TFs) binding to genomic regulatory elements and recruiting regulatory cofactors (CoFs). Therefore, to understand specificity in gene regulation, we must address how TF-DNA binding translates into target gene specificat...

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Bibliographic Details

Main Author:	Keenan, Jessica Lynn
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01-01-2019
Subjects:	Bioinformatics Biology Molecular biology
Online Access:	Get full text
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