The enterohaemorrhagic Escherichia coli effector EspW triggers actin remodelling in a Rac1 dependent manner

Enterohaemorrhagic Escherichia coli (EHEC) is a diarrheagenic pathogen that colonizes the gut mucosa by forming attaching-and-effacing lesions. EHEC employs a type III secretion system (T3SS) to translocate 50 effector proteins that hijack and manipulate host cell signalling pathways, which contribu...

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Bibliographic Details

Main Author:	Sandu, Pamela
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01-01-2017
Subjects:	E coli Infections
Online Access:	Get full text
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