Chemical constituents from the flowers of Satsuma mandarin and their free radical scavenging and [alpha]-glucosidase inhibitory activities

Flowers of Citrus plants are used as mild sedatives and for the treatment of insomnia in traditional medicines. In Japan, tea made from the flowers of Satsuma mandarin is consumed as healthy drink. Hesperidin (1), hesperetin (2), rutin (3), quercetin (4), nicotiflorin (5), eriocitrin (6), narirutin...

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Bibliographic Details
Published in:	Natural product research Vol. 33; no. 11; p. 1670
Main Authors:	Adhikari-Devkota, Anjana, Elbashir, Sara Mustafa Idris, Watanabe, Takashi, Devkota, Hari Prasad
Format:	Journal Article
Language:	English
Published:	Abingdon Taylor & Francis Ltd 01-06-2019
Subjects:	Citrus reticulata Flowers Free radicals Glucosidase Hesperidin Insomnia Mandarins NMR Nuclear magnetic resonance Organic chemistry Plants (botany) Quercetin Rutin Scavenging Sedatives Sleep disorders Tea α-Glucosidase
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Summary:	Flowers of Citrus plants are used as mild sedatives and for the treatment of insomnia in traditional medicines. In Japan, tea made from the flowers of Satsuma mandarin is consumed as healthy drink. Hesperidin (1), hesperetin (2), rutin (3), quercetin (4), nicotiflorin (5), eriocitrin (6), narirutin (7), phenylethyl glucoside (8) and unshuoside A (9) were isolated from the MeOH extract of fresh flowers. Structure elucidation of these compounds was performed on the basis of NMR spectroscopic data. Among them, rutin (3), quercetin (4) and eriocitrin (6) showed potent free radical scavenging activity, whereas hesperetin (2) and quercetin (4) showed potent α-glucosidase inhibitory activity.
ISSN:	1478-6419 1478-6427
DOI:	10.1080/14786419.2018.1425856