Osteopontin expression is essential for interferon-[alpha] production by plasmacytoid dendritic cells

The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells (pDCs) suggests that Opn might contribute to the expression of interferon-alpha (IFN-alpha) in those cells. Here we show that Opn deficiency su...

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Bibliographic Details

Published in:	Nature immunology Vol. 7; no. 5; p. 498
Main Authors:	Shinohara, Mari L, Lu, Linrong, Bu, Jing, Werneck, Miriam B F, Kobayashi, Koichi S, Glimcher, Laurie H, Cantor, Harvey
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group 01-05-2006
Subjects:	Translocation
Online Access:	Get full text
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