Tau and GSK3[beta] Dephosphorylations are Required for Regulating Pin1 Phosphorylation

Pin1 binds mitotically phosphorylated Thr231-Pro232 and Thr212-Pro213 sites on tau, and a Pin1 deficiency in mice leads to tau hyperphosphorylation. The aim of this study was to determine if the dephosphorylation or inhibition of tau and GSK3[beta] phosphorylation induces the Pin1 phosphorylation. T...

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Bibliographic Details
Published in:Neurochemical research Vol. 30; no. 8; p. 955
Main Authors: Min, Sae H, Cho, Jung S, Oh, Jae H, Shim, Sun B, Hwang, Dae Y, Lee, Su H, Jee, Seung W, Lim, Hwa J, Kim, Min Y, Sheen, Yhun Y, Lee, Seok H, Kim, Yong K
Format: Journal Article
Language:English
Published: New York Springer Nature B.V 01-08-2005
Online Access:Get full text
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