Investigation of Potential Targets for Gene Therapy in Acute Myeloid Leukaemia: Targeting PML/RARα Transcript by DNAzymes

The effects of ribozymes have been investigated in a number of leukaemias. More recently, increased interest was shown in the activity of new molecules called DNAzymes. Acute promyelocytic leukaemia (APL) is characterized by the reciprocal translocation t(15;17) which produces the fusion gene PML/RA...

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Bibliographic Details

Main Author:	Kabuli, Majid
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01-01-2004
Subjects:	Biochemistry Medicine Molecular biology
Online Access:	Get full text
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