A "latent niche" mechanism for tumor initiation

Stem cells, their niches, and their relationship to cancer are under intense investigation. Because tumors and metastases acquire self-renewing capacity, mechanisms for their establishment may involve cell-cell interactions similar to those between stem cells and stem cell niches. On the basis of ou...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS Vol. 106; no. 28; p. 1617
Main Authors: McGovern, Marie, Voutev, Roumen, Maciejowski, John, Corsi, Ann K, Hubbard, E Jane Albert
Format: Journal Article
Language:English
Published: Washington National Academy of Sciences 14-07-2009
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