Lycopene affects hepatic gene expression of the main antioxidant enzymes in gilts

• Published in: Journal of animal science Vol. 95; p. 344
• Main Authors: Fachinello, M R, Partyka, A V S, Khatlab, A D S, Gasparino, E, Nunes, R V, Pozza, P C
• Format: Journal Article
• Language: English
• Published: Champaign Oxford University Press 01-08-2017
• Subjects: Antioxidants; Catalase; Chemical compounds; Diet; Enzymes; Gene expression; Hogs; Liver; Lycopene; Redox properties
• ISSN: 0021-8812; 1525-3163
• DOI: 10.2527/asasann.2017.706

An abstract of a study by Fachinello et al evaluating the effects of lycopene 10% extract levels in the diet of pigs, barrows, and gilts on the gene expression of antioxidant enzymes in the liver is presented. Lycopene levels didn't influence the GLPx gene expression in the liver of the pigs, but the gilts presented a lower gene expression in relation to the barrows. These results indicate that lycopene may reduce the expression of antioxidant enzymes as a result of an adjustment of the cellular redox state due to the consumption of an exogenous antioxidant. It was concluded that lycopene reduced the gene expression of SOD and catalase enzymes in gilts' liver.