Erosion of the chronic myeloid leukaemia stem cell pool by PPAR[gamma] agonists

Whether cancer is maintained by a small number of stem cells or is composed of proliferating cells with approximate phenotypic equivalency is a central question in cancer biology. In the stem cell hypothesis, relapse after treatment may occur by failure to eradicate cancer stem cells. Chronic myeloi...

Full description

Bibliographic Details

Published in:	Nature (London) Vol. 525; no. 7569; p. 380
Main Authors:	Prost, Stéphane, Relouzat, Francis, Spentchian, Marc, Ouzegdouh, Yasmine, Saliba, Joseph, Massonnet, Gérald, Beressi, Jean-Paul, Verhoeyen, Els, Raggueneau, Victoria, Maneglier, Benjamin, Castaigne, Sylvie, Chomienne, Christine, Chrétien, Stany, Rousselot, Philippe, Leboulch, Philippe
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group 17-09-2015
Subjects:	Bone marrow Cell division Cytokines Leukemia Phosphorylation Stem cells Translocation
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!