Silica-Supported Tungstic Acid Catalyzed Synthesis and Antioxidant Activity of [alpha]-Hydroxyphosphonates

Silica-Supported Tungstic Acid Catalyzed Synthesis and Antioxidant Activity of [alpha]-Hydroxyphosphonates

A green and efficient method has been accomplished for the synthesis of α-hydroxyphosphonates using silica-supported tungstic acid (STA) as a heterogeneous catalyst under solvent-free conditions at ambient temperature. The compounds obtained were characterized by spectral and analytical studies and...

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Bibliographic Details
Published in:Phosphorus, sulfur, and silicon and the related elements Vol. 190; no. 9; p. 1479
Main Authors: Santhisudha, S, Sreelakshmi, P, Jayaprakash, S. H, Vijaya Kumar, B, Suresh Reddy, C
Format: Journal Article
Language:English
Published: Abingdon Taylor & Francis Ltd 01-09-2015
Subjects:
Acids
Antioxidants
Free radicals
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Summary:A green and efficient method has been accomplished for the synthesis of α-hydroxyphosphonates using silica-supported tungstic acid (STA) as a heterogeneous catalyst under solvent-free conditions at ambient temperature. The compounds obtained were characterized by spectral and analytical studies and screened in vitro for the antioxidant activity by four methods viz., DPPH free radical scavenging assay, hydrogen peroxide scavenging assay, NO method, FRAP method. The results indicated that the title compounds are potential antioxidants and are comparable to the antioxidant property of the standard ascorbic acid.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426507.2014.991825