Inhibition of [alpha]5[beta]1-integrin significantly improves the surgical outcome of glaucoma surgery in mice compared to MMC

Purpose The aim of this study was to evaluate the therapeutic potential of [alpha]5[beta]1-integrin inhibitor (CLT-28643) to improve the outcome of filtering surgery in a mouse model. Different dose regimen and administration routes of the inhibitor were compared to mitomycin C (MMC), the gold stand...

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Bibliographic Details
Published in:	Acta ophthalmologica (Oxford, England) Vol. 92; no. s253
Main Authors:	Van Bergen, T, Zahn, G, Caldirola, P, Fsadni, M, CARAM-LELHAM, N, Vandewalle, E, Stalmans, I
Format:	Journal Article
Language:	English
Published:	Malden Wiley Subscription Services, Inc 01-09-2014
Subjects:	Ophthalmology
Online Access:	Get full text
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