Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16E6andE7genes

An effective vaccine for treating human papillomavirus (HPV)-associated malignancies such as cervical cancer should elicit strong T cell-mediated immunity (CMI) against the E6 and/or E7 proteins necessary for the malignant state. We have developed Venezuelan equine encephalitis (VEE) virus replicon...

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Bibliographic Details
Published in:	Vaccine Vol. 22; no. 3; p. 520
Main Authors:	Cassetti, MCristina, McElhiney, Sue P, Shahabi, Vafa, Pullen, Jeffrey K, Le Poole, ICaroline, Eiben, Gretchen L, Smith, Larry R, Kast, WMartin
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Limited 02-01-2004
Subjects:	Amino acids Apoptosis Cervical cancer Cytotoxicity Deoxyribonucleic acid Disease DNA Human papillomavirus Immunogenicity Inactivation Infections Lymphocytes Mutagenesis Mutation Proteins Rodents Tumors Vaccines
Online Access:	Get full text
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