Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp sequence of fibrinogen. (Aminobenzamidino)succinyl (ABAS) series of orally activ fibrinogen receptor antagonists

Saved in:

Bibliographic Details
Published in:	Journal of medicinal chemistry Vol. 38; no. 13; pp. 2378 - 2394
Main Authors:	ZABLOCKI, J. A, RICO, J. G, TOTH, M. V, ZUPEC, M. E, MCMACKINS, D. E, ADAMS, S. P, MIYANO, M, MARKOS, C. S, MILTON, M. N, PAULSON, S, HERIN, M, JACQMIN, P, GARLAND, R. B, NICHOLSON, N. S, PANZER-KNODLE, S. G, HAAS, N. F, PAGE, J. D, SZALONY, J. A, TAITE, B. B, SALYERS, A. K, KING, L. W, CAMPION, J. G, FEIGEN, L. P, ROGERS, T. E, WILLIAMS, K, SCHRETZMAN, L. A, RAO, S. A, BOVY, P. R, TJOENG, F. S, LINDMARK, R. J
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 1995
Subjects:	Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Medical sciences Pharmacology. Drug treatments Intravenous administration Modeling Aminoester Ex vivo Structure activity relation Fibrinogen Molecular model Force field method Dicarboxylic acid Antagonist Chemical synthesis Dog Biological receptor Fissipedia Carnivora Benzene derivatives Oral administration Prodrug In vitro Antiplatelet agent In vivo Vertebrata Amidine Mammalia Aminoacid Animal Carboxamide Pharmacokinetics
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
ISSN:	0022-2623 1520-4804