Rapid LC-ESI-MS-MS Method for the Simultaneous Determination of Clopidogrel and its Carboxylic Acid Metabolite in Human Plasma : Biological samples
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| Published in: | Journal of chromatographic science Vol. 46; no. 10; pp. 867 - 875 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
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Niles, IL
Preston Publications
2008
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| Author | KUNDLIK, Mohan SHRIVASTAV, Pranav S SUBBAIAH, Gunta SHAH, Hiten PATEL, Nitesh K |
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| Author_xml | – sequence: 1 givenname: Nitesh K surname: PATEL fullname: PATEL, Nitesh K organization: Chemistry Department, School of Sciences, Gujarat University, Navrangpura, Ahmedabad 380 009, India – sequence: 2 givenname: Gunta surname: SUBBAIAH fullname: SUBBAIAH, Gunta organization: Bioanalytical Laboratory, Torrent Research Center, At Village Bhat, Gandhinagar 382 428, India – sequence: 3 givenname: Hiten surname: SHAH fullname: SHAH, Hiten organization: Bioanalytical Laboratory, Torrent Research Center, At Village Bhat, Gandhinagar 382 428, India – sequence: 4 givenname: Mohan surname: KUNDLIK fullname: KUNDLIK, Mohan organization: Bioanalytical Laboratory, Torrent Research Center, At Village Bhat, Gandhinagar 382 428, India – sequence: 5 givenname: Pranav S surname: SHRIVASTAV fullname: SHRIVASTAV, Pranav S organization: Chemistry Department, School of Sciences, Gujarat University, Navrangpura, Ahmedabad 380 009, India |
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| Keywords | Solid phase extraction Biological fluid Tandem mass spectrometry Chemical analysis Metabolite HPLC chromatography Anticoagulant Electrospray Blood Chemical enrichment Blood plasma Ester Sample preparation Carboxylic acid Quantitative analysis Human Validation Coupled method Oral administration Bioavailability Normal Antiplatelet agent Simultaneous measurement Clopidogrel Thienopyridine derivative Pharmacokinetics |
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| StartPage | 867 |
| SubjectTerms | Analysis Biological and medical sciences General pharmacology Medical sciences Pharmacology. Drug treatments |
| Title | Rapid LC-ESI-MS-MS Method for the Simultaneous Determination of Clopidogrel and its Carboxylic Acid Metabolite in Human Plasma : Biological samples |
| Volume | 46 |
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