Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors undertreatment with imatinib mesylate

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Published in:	Clinical cancer research Vol. 12; no. 6; pp. 1743 - 1749
Main Authors:	WARDELMANN, Eva, MERKELBACH-BRUSE, Sabine, REICHARDT, Peter, HOHENBERGER, Peter, PAULS, Katharina, THOMAS, Nadja, SCHILDHAUS, Hans-Ulrich, HEINICKE, Thomas, SPEIDEL, Nicola, PIETSCH, Torsten, BUETTNER, Reinhard, PINK, Daniel
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA American Association for Cancer Research 2006
Subjects:	Antineoplastic agents Biological and medical sciences Gastroenterology. Liver. Pancreas. Abdomen Medical sciences Pharmacology. Drug treatments Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Antineoplastic agent Clonality Imatinib Secondary Enzyme Transferases Enzyme inhibitor Gastrointestinal stromal tumor Digestive diseases Evolution Mutation Protein-tyrosine kinase kit Gene
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Author	PAULS, Katharina HEINICKE, Thomas REICHARDT, Peter THOMAS, Nadja BUETTNER, Reinhard MERKELBACH-BRUSE, Sabine SPEIDEL, Nicola HOHENBERGER, Peter PIETSCH, Torsten WARDELMANN, Eva SCHILDHAUS, Hans-Ulrich PINK, Daniel
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Keywords	Antineoplastic agent Clonality Imatinib Secondary Enzyme Transferases Enzyme inhibitor Gastrointestinal stromal tumor Digestive diseases Evolution Mutation Protein-tyrosine kinase kit Gene
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SubjectTerms	Antineoplastic agents Biological and medical sciences Gastroenterology. Liver. Pancreas. Abdomen Medical sciences Pharmacology. Drug treatments Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Title	Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors undertreatment with imatinib mesylate
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