Antimicrobial Constituents from the Bacillus megaterium LC Isolated from Marine Sponge Haliclona oculata

Antimicrobial Constituents from the Bacillus megaterium LC Isolated from Marine Sponge Haliclona oculata

Three compounds including 7,7-bis(3-indolyl)-p-cresol (1), cyclo-(S-Pro-R-Leu) (2) and cyclo-(S-Pro-R-Val) (3) were isolated from the strain of Bacillus megaterium LC derived from the marine sponge Haliclona oculata. All the isolated compounds showed antimicrobial activity at MIC values ranging from...

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Bibliographic Details
Published in:Natural product sciences Vol. 20; no. 3; pp. 202 - 205
Main Authors: Pham, Viet Cuong, Nguyen, Thi Kim Cuc, Vu, Thi Quyen, Pham, Thanh Binh, Phan, Van Kiem, Nguyen, Hoai Nam, Nguyen, Tien Dat
Format: Journal Article
Language:Korean
Published: 2014
Subjects:
antimicrobial
sponge-associated bacteria
Haliclona oculata
Bacillus megaterium
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Summary:Three compounds including 7,7-bis(3-indolyl)-p-cresol (1), cyclo-(S-Pro-R-Leu) (2) and cyclo-(S-Pro-R-Val) (3) were isolated from the strain of Bacillus megaterium LC derived from the marine sponge Haliclona oculata. All the isolated compounds showed antimicrobial activity at MIC values ranging from 0.005 to $5{\mu}g/mL$ against Gram-negative bacteria Vibrio vulnificus and V. parahaemolyticus, gram-positive bacteria Bacillus cereus and Micrococcus luteus, and the dermatophyte Trichophyton mentagrophytes. The results suggested that these compounds might have potential to be developed as agents treating dermatosis and controlling vibriosis in aquaculture.
Bibliography:KISTI1.1003/JNL.JAKO201430754388385
ISSN:1226-3907