Seasonal Influence on Phenolic-mediated Antihyperglycemic Properties of Canadian Sugar and Red Maple Leaves Using in vitro Assay Models

• Published in: Food science and biotechnology Vol. 21; no. 3; pp. 753 - 760
• Main Authors: Apostolidis, Emmanouil, Li, Liya, Kang, Bou-Hee, Lee, Chong-M, Seeram, Navindra P
• Format: Journal Article
• Language: Korean
• Published: 2012
• Subjects: {\alpha}$-glucosidase; {\alpha}$-amylase; sugar maple; red maple; phenolic profile
• ISSN: 1226-7708; 2092-6456

Red and sugar maple leaves collected in the summer and fall from Canada, were evaluated for phenolic content, antioxidant, ${\alpha}$-glucosidase, and ${\alpha}$-amylase inhibitory activities variation. The phenolic contents of summer red maple leaves (RML-S) and summer sugar maple leaves (SML-S) were higher than red and sugar maple leaves collected in fall (RML-F and SML-F, respectively). HPLC analyses showed differences in phenolic compounds present in the SML samples compared to the RML samples. The extracts were assayed for yeast and rat ${\alpha}$-glucosidase inhibitory activities. Both results showed that SML-S extracts had the highest inhibitory activity which could possibly be attributed to the unique phenolics present therein. Milder effects were observed in terms of ${\alpha}$-amylase inhibitory activity, with RML-F having the highest inhibitory activity. These results suggest that maple tree leaf extracts may have potential for phenolic-mediated ${\alpha}$-glucosidase inhibition, relevant to type 2 diabetes management, with SML-S extract having the highest bioactivity.