α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling

Antiangiogenesis therapies are now part of the standard repertoire of cancer therapies, but the mechanisms for the proliferation and survival of endothelial cells are not fully understood. Although endothelial cells are covered with a glycocalyx, little is known about how endothelial glycosylation r...

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Bibliographic Details
Published in:The Journal of biological chemistry Vol. 285; no. 9; p. 6515
Main Authors: Shinobu Kitazume, Rie Imamaki, Kazuko Ogawa, Yusuke Komi, Satoshi Futakawa, Soichi Kojima, Yasuhiro Hashimoto, Jamey D. Marth, James C. Paulson, Naoyuki Taniguchi
Format: Journal Article
Language:English
Published: American Society for Biochemistry and Molecular Biology 26-02-2010
Online Access:Get full text
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