Decorin Regulates Endothelial Cell Motility on Collagen I through Activation of Insulin-like Growth Factor I Receptor and Modulation of α2β1 Integrin Activity

The proteoglycan decorin is expressed by sprouting but not quiescent endothelial cells, and angiogenesis is dysregulated in its absence. Previously, we have shown that decorin core protein can bind to and activate insulin-like growth factor-I receptor (IGF-IR) in endothelial cells. In this study, we...

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Bibliographic Details

Published in:	The Journal of biological chemistry Vol. 283; no. 25; p. 17406
Main Authors:	Lorna R. Fiedler, Elke Schönherr, Rachel Waddington, Stephan Niland, Daniela G. Seidler, Daniel Aeschlimann, Johannes A. Eble
Format:	Journal Article
Language:	English
Published:	American Society for Biochemistry and Molecular Biology 20-06-2008
Online Access:	Get full text
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