Matrices of Paired Substitutions Show the Effects of tRNA D/T Loop Sequence on Drosophila RNase P and 3′-tRNase Processing

Drosophila RNase P and 3′-tRNase endonucleolytically process the 5′ and 3′ ends of tRNA precursors. We examined the processing kinetics of normal substrates and the inhibitory effect of the tRNA product on both processing reactions. The product is not a good RNase P inhibitor, with a K I appro...

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Bibliographic Details
Published in:The Journal of biological chemistry Vol. 273; no. 2; p. 1015
Main Authors: Louis Levinger, Rae Bourne, Srinivas Kolla, Edruge Cylin, Kirk Russell, Xudong Wang, Amulya Mohan
Format: Journal Article
Language:English
Published: American Society for Biochemistry and Molecular Biology 09-01-1998
Online Access:Get full text
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