Correlation between Fecal Concentrations of Ciprofloxacin and Fecal Counts of Resistant Enterobacteriaceae in Piglets Treated with Ciprofloxacin: toward New Means To Control the Spread of Resistance? CIPROFLOXACIN LEVELS AND RESISTANT BACTERIA IN FECES

We assessed in a piglet model the relationship between fecal ciprofloxacin concentrations and ciprofloxacin-resistant Enterobacteriaceae counts. Twenty-nine piglets were orally treated with placebo or with 1.5 or 15 mg ciprofloxacin/kg of body weight/day from day 1 (D1) to D5. Areas under the curve...

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Bibliographic Details

Published in:	Antimicrobial agents and chemotherapy Vol. 56; no. 9; pp. 4973 - 5
Main Authors:	Nguyen, Thu Thuy, Chachaty, Elisabeth, Huy, Clarisse, Cambier, Carole, de Gunzburg, Jean, Mentré, France, Andremont, Antoine
Format:	Journal Article
Language:	English
Published:	American Society for Microbiology 01-09-2012
Subjects:	Bioinformatics Computer Science Human health and pathology Infectious diseases Life Sciences Quantitative Methods fecal concentration fluoroquinolone bacterial resistance ciprofloxacin Enterobacteriaceae pharmacokinetic/pharmacodynamic relationship
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