Catalytic hydrotrifluoromethylation of unactivited alkenes

Catalytic hydrotrifluoromethylation of unactivited alkenes

A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is disclosed. This effective transformation operates at room temperature in the presence of 5 mol % Ru(bpy)3Cl2; the process is characterized by its ope...

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Bibliographic Details
Published in:Journal of the American Chemical Society Vol. 135; no. 7
Main Authors: Mizuta, Satoshi, Verhoog, Stefan, Engle, Keary M., Khotavivattana, Tanatorn, O’duill, Miriam, Wheelhouse, Katherine, Rassias, Gerasimos, Médebielle, Maurice, Gouverneur, Véronique
Format: Journal Article
Language:English
Published: American Chemical Society 2013
Subjects:
Chemical Sciences
Organic chemistry
Online Access:Get full text
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Summary:A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is disclosed. This effective transformation operates at room temperature in the presence of 5 mol % Ru(bpy)3Cl2; the process is characterized by its operational simplicity and functional group tolerance.
ISSN:0002-7863
1520-5126