sup.99Mo/.sup.99mTc generators based on aluminum molybdate gel matrix prepared by nano method

• Published in: Journal of radioanalytical and nuclear chemistry Vol. 318; no. 2; p. 915
• Main Authors: Amin, M, El-Amir, M. A, Ramadan, H. E, El-Said, H
• Format: Journal Article
• Language: English
• Published: Springer 01-11-2018
• ISSN: 0236-5731
• DOI: 10.1007/s10967-018-6141-5

A procedure for preparation of .sup.99Mo/.sup.99mTc radioisotope generator based on low specific activity neutron activated .sup.99Mo was developed. Aluminum molybdate(VI)-.sup.99Mo of high Mo(VI) content (~ 364 mg/g Al.sup.99Mo) was prepared by mixing low specific activity molybdate(VI)-.sup.99Mo and aluminum mixture solution with isoamyl alcohol. Al.sup.99Mo gel matrix was precipitated when the pH of the mixture solution was raised to ~ 5 by addition of NaOH to the mixture. Radiometric measurements indicate the strong fixation of Molybdate(VI)-.sup.99Mo species in the form of the sparingly insoluble Al.sup.99Mo gel matrix. The prepared AlMo gel matrix was physiochemically characterized. Al.sup.99Mo gel matrix was used as a base material for preparation of .sup.99Mo/.sup.99mTc generator. The .sup.99mTc eluted from .sup.99Mo/.sup.99mTc radioisotope generator was found to have relatively high elution yield (84 ± 2.3%), radionuclidic ([greater than or equal to] 99.99%), radiochemical (98.1 ± 0.9%) and chemical purity.