Effect of hyperbaric re-respiration on condition of nonspecific protective mechanisms of the body of troops suffering from chronic prostatitis

• Published in: Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik no. 2; pp. 48 - 55
• Main Authors: K. G. Golendukhin, S. V. Poroyskiy, I. V. Karabach, V. Yu. Skokova, S. M. Groshilin
• Format: Journal Article
• Language: Russian
• Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 01-04-2016
• Subjects: abacterial chronic prostatitis; hyperbaric re-respiration; military serviceman; nonspecific resistance mechanisms; абактериальный хронический простатит; военнослужащие; гипербарическая ререспирация; неспецифическая резистентность
• EISSN: 2541-9544
• ISSN: 1608-6228

The research objective is an assessment of effectiveness of hyperbaric re-respiration (HRR) in treatment of military servicemen suffering from chronic abacterial prostatitis (CAP). The research type is prospective (cohort), clinical and physiological. The subjects are 38 patients with CAP in the acute phase (category III A and III B), aged 32-46, were randomly allocated into 3 groups depending on the kind of therapy: the control group - conventional treatment of CAP in the acute phase (n = 10); the comparison group (n = 14) - traditional therapy and 12-14 hyperbaric oxygen therapy treatments (35-40-minute stay in the oxygen chamber at a pressure of about 153 kPa); the treatment group (n = 14) - the traditional therapy and a course of HRR (12-14 treatments, 35-40 minute stay under the conditions of higher oxygen (27.9 kPa) and carbon dioxide (3.4 kPa) partial pressure produced in the pressure chamber at a total pressure of about 153 kPa). All patients before treatment, after his graduation, and then six months later determined the indices of phagocyte activity of neutrophils, which are judged on the state of nonspecific resistance. Initial examination revealed a clear shortage of nonspecific protective mechanisms in most patients. Spent treatment accompanied by statistically significant increases in aerobic and anaerobic phagocyte activity only in patients of the treatment group that has resulted in significant inter-group differences of the studied parameters. Through 6 months in patients of the treatment group registered a further increase in the activity of aerobic and anaerobic mechanisms of phagocytosis in the absence of such trends in the other two groups. Therefore, the appointment of HRR promotes activation of nonspecific resistance mechanisms in patients with CAP, which contributes to extension of relapse-free period in the course of the disease.