Alcalóides pirrolizidínicos em espécies do gênero Senecio

Alcalóides pirrolizidínicos em espécies do gênero Senecio

Senecio species contain a large variety of secondary metabolites and many of these plants afford pyrrolizidine alkaloids. This paper is a review of the literature, describing 62 pyrrolizidine alkaloids already isolated in 62 of more than 2000 species of Senecio, distributed worldwide. The structure-...

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Bibliographic Details
Published in:Química Nova Vol. 29; no. 5; pp. 1047 - 1053
Main Authors: Chana de Medeiros da Silva, Aline Abati Bolzan, Berta Maria Heinzmann
Format: Journal Article
Language:English
Published: Sociedade Brasileira de Química 01-10-2006
Subjects:
hepatotoxicity
pyrrolizidine alkaloids
Senecio
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Summary:Senecio species contain a large variety of secondary metabolites and many of these plants afford pyrrolizidine alkaloids. This paper is a review of the literature, describing 62 pyrrolizidine alkaloids already isolated in 62 of more than 2000 species of Senecio, distributed worldwide. The structure-activity relationships involving their toxicity are also discussed, since some Senecio species used for medicinal purposes are responsible for causing serious adverse effects.
ISSN:1678-7064
DOI:10.1590/S0100-40422006000500026