芝麻素与细辛素检测方法及生物活性的研究进展Progress on detection methods and physiological activities of sesamin and asarinin

• Published in: Zhongguo you zhi Vol. 49; no. 5; pp. 138 - 143
• Main Author: 余琼，刘华敏，汪学德 YU Qiong, LIU Huamin, WANG Xuede
• Format: Journal Article
• Language: English
• Published: 中粮工科（西安）国际工程有限公司 01-05-2024
• Subjects: sesamin; asarinin; detection method; physiological activity; 芝麻素；细辛素；检测方法；生物活性
• ISSN: 1003-7969
• DOI: 10.19902/j.cnki.zgyz.1003-7969.210279

旨在为芝麻木酚素相关产品、特殊用途油脂等的研发提供参考，对芝麻木酚素中主要的脂溶性活性成分芝麻素及其转化产物细辛素的含量分布、转化条件、检测方法和生物活性进行综述。芝麻素是芝麻中含量最多的脂溶性木酚素，而芝麻中几乎不含细辛素，但芝麻素可在酸性和受热条件下转化为细辛素；芝麻素与细辛素的检测方法有高效液相色谱法、薄层色谱法、气相色谱-质谱联用法、液相色谱-质谱联用法等；芝麻素具有抑菌、抗癌、降血脂等生物活性，细辛素具有抗炎、抑菌、抗病毒、抗癌、抗肿瘤、抗氧化等生物活性。In order to provide references for the research and development of sesame lignan-related products and oils for special purposes, the contents, convertion conditions, detection methods and physiological activities of sesamin and asarinin were reviewed. Sesamin is the most abundant fat-soluble lignan in sesame, while asarinin is almost absent in sesame, but sesamin can be converted to asarinin under acidic and heat conditions. Sesamin and asarinin can be detected by high performance liquid chromatography, thin layer chromatography, gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, etc. Sesamin has bioactivities such as antibacterial, anticancer and hypolipidemic, and asarinin has bioactivities such as anti-inflammatory, antibacterial, antiviral, anticancer, antitumor, and antioxidant.