Dysembryoplastic neuroepithelial tumor and oligodendroglioma: the diagnostic value of magnetic resonance spectroscopy Case report and review of the literature

• Published in: Neurosurgical focus Vol. 4; no. 4; p. E8
• Main Authors: Sherburn, Eric W., Bahn, Mark M., Gokden, Murat, Silbergeld, Daniel L., Rich, Keith M.
• Format: Journal Article
• Language: English
• Published: 01-04-1998
• ISSN: 1092-0684; 1092-0684
• DOI: 10.3171/foc.1998.4.4.9

Preoperative differentiation between dysembryoplastic neuroepithelial tumor (DNT) and low-grade glioma is often not possible. Dysembryoplastic neuroepithelial tumor is a recently described entity of uncertain origin; however, the diagnosis has important clinical implications. Clinical and radiological findings of DNT and low-grade glioma, especially oligodendroglioma, may be similar. Treatment options and prognosis differ significantly between these two lesions; consequently, accurate diagnosis is imperative. The authors describe two individuals who presented simultaneously at their institution: one patient with an oligodendroglioma and a second patient with DNT. The natural history, neurodiagnostic, and pathological features of each are reviewed with special emphasis on the potential utility of magnetic resonance spectroscopy in differentiating these lesions.