COMPARISON OF INSULIN RESISTANCE WITH THE SEVERITY OF METABOLIC SYNDROME

• Published in: Asian journal of pharmaceutical and clinical research pp. 73 - 75
• Main Authors: N, BHAGYASHREE, C, RAMASWAMY, K, RAMYA, M, GANESH
• Format: Journal Article
• Language: English
• Published: 19-06-2020
• ISSN: 0974-2441; 0974-2441
• DOI: 10.22159/ajpcr.2020.v13i9.38444

Objective: Insulin resistance (IR) means a reduced ability of insulin to stimulate glucose utilization. IR is related to cardiovascular disease (CVD) risk as the IR forms the basis for atherogenesis and acts as a major risk factor for atherosclerotic CVD.
Methods: Total of 195 participants were recruited divided into three groups based on the presence of metabolic abnormalities as control Group I (with <3 components of metabolic syndrome [MS]), MS group as Group II (with any 3 components of MS), and severe MS as Group III (with more than three components of MS).
Results: Results showed that fasting blood sugar (FBS) and glycated hemoglobin showed a significant difference between the groups (p<0.001), whereas fasting insulin and IR were higher in severe MS which showed statistically significant difference (p<0.001) in comparison with control and MS group.
Conclusion: IR is one of the principal factors for the development of MS and further threw light that the increase in the IR level proportionately increases the severity of MS.