EFFECTS OF HIBISCUS SABDARIFFA L. CONSUMPTION DURING PREGNANCY ON BIOCHEMICAL PARAMETERS AND LITTER BIRTH WEIGHT IN RATS

• Published in: African journal of traditional, complementary, and alternative medicines Vol. 12; no. 5; pp. 79 - 83
• Main Authors: Eghosa, Iyare E., Charles, Ezeh O., Thomas, Nubilla, Ifeoma, Orizu A.
• Format: Journal Article
• Language: English
• Published: 31-07-2015
• ISSN: 0189-6016; 2505-0044
• DOI: 10.21010/ajtcam.v12i5.12

Background: Extracts of Hibiscus sabdariffa L. (HS; family: Malvaceae) are widely believed in folk medicine to be effective in the treatment of
a variety of ailments. In Nigeria, anecdotal reports by women who consume HS during pregnancy suggest that they consume it because of the
folkloric belief that it makes them “feel lighter”. This study aimed to investigate the effect of maternal consumption of HS during pregnancy on
litter birth weight and the functional integrity of the liver of pregnant rats.
Materials and Methods: Thirty-six rats aged twelve to fourteen weeks were used. On day 1 of pregnancy, the rats were randomly assigned to
three groups. Group A were given tap water, group B were given 0.6g/100ml while group C were given 1.8g/100ml of the extract. On day 18 of
pregnancy, blood samples were taken for determination of Serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate
transaminase (SGPT), alkaline phosphatase, urea and creatinine.
Results: Gestational length, litter size and birth weights were recorded at delivery. HS consumption did not affect (P>0.05) SGOT level but
increased (P