Abstract B10: Cyclin D1 restrains oncogene-induced autophagy via phosphorylation of LKB1

Abstract Cyclin D1 is an important molecular driver of many human cancers. The cyclin D1 gene is amplified or overexpressed in up to half of human breast cancers and mammary-targeted overexpression of cyclin D1 is sufficient to induce mammary tumorigenesis in mice. Cyclin D1 encodes the regulatory s...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 76; no. 3_Supplement; p. B10
Main Authors:	Casimiro, Mathew, Sante, Gabriele Di, Loro, Emanuele, Pestell, Timothy, Bisetto, Sara, Velasco-Velázquez, Marco, Jiao, Xuanmao, Li, Zhiping, Wang, Chenguang, Ly, Daniel, Zheng, Bin, Che-Hung, Shen, Ertel, Adam, Pestell, Richard G.
Format:	Journal Article
Language:	English
Published:	01-02-2016
Online Access:	Get full text
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