Abstract 5702: BTX-9341, a bifunctional degrader of CDK4 and CDK6 for glioblastoma multiforme

Abstract Glioblastoma multiforme (GBM) is an aggressive form of brain cancer with limited treatment options. GBM has a high frequency of dysregulation of the CDKN2A-cyclin D-CDK4/CDK6 signaling node and should subsequently be sensitive to CDK4/6 inhibition. Despite this, the CDK4/6 inhibitors that a...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 84; no. 6_Supplement; p. 5702
Main Authors:	Majeski, Hannah, Chahal, Kirti, Okano, Akinori, Pasis, Angela, Carlson, Casey, Shakya, Arvind, Liu, Qiao, Huang, Shenlin, Chourasia, Aparajita Hoskote, Fung, Leah
Format:	Journal Article
Language:	English
Published:	22-03-2024
Online Access:	Get full text
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