Abstract 4666: PDX, mini-brain co-cultures and patient-derived tumor organoids: Preclinical models to study the prion protein in glioblastoma biology

Glioblastoma (GBM), supported by a subpopulation of glioblastoma stem cells (GSCs), stands among the most harmful tumors. Its invasive and aggressive behavior has been correlated with poor therapy outcomes and reduced patient survival, which remains difficult to model and treat due to its cellular a...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 4666
Main Authors:	Souza, Maria Clara da Silva, Coelho, Barbara P., Fernandes, Camila F., Santos, Tiago G. Dos, Knorst, Stefan, Masotti, Cibele, Passos-Bueno, Maria Rita S., Lopes, Marilene H.
Format:	Journal Article
Language:	English
Published:	04-04-2023
Online Access:	Get full text
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