Abstract 4539: Tumor evolution and immune microenvironment dynamics define response to neoadjuvant treatment of esophageal adenocarcinoma

Introduction: Locally advanced esophageal adenocarcinoma (EAC) remains difficult to treat, and resistance is common. The ecological and evolutionary dynamics responsible for treatment failure are incompletely understood. Aim & Methods: We performed a multi-omic study with a multi-timepoint strat...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 4539
Main Authors:	Barroux, Melissa, Househam, Jacob, Lakatos, Eszter, Ronel, Tahel, Baker, Ann-Marie, Salié, Henrike, Mossner, Max, Smith, Kane, Kimberley, Chris, Nowinski, Salpie, Berner, Alison, Gunasri, Vinaya, Jansen, Marnix, Caravagna, Giulio, Slotta-Huspenina, Julia, Weichert, Wilko, Alberstmeier, Markus, Chain, Benny, Friess, Helmut, Bengsch, Bertram, Schmid, Roland M., Siveke, Jens T., Quante, Michael, Graham, Trevor A.
Format:	Journal Article
Language:	English
Published:	04-04-2023
Online Access:	Get full text
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