Abstract 1831: Affinity tuned XmAb®2+1 GPC3 x CD3 bispecific antibodies demonstrate selective activity in liver cancer models

Bispecific T cell engagers simultaneously bind CD3 on T cells and tumor-associated antigens to promote T cell-mediated killing of tumor cells. These agents provide synthetic immunity by expanding, activating, and redirecting T cells against a target of interest. While targeting lineage-restricted an...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 81; no. 13_Supplement; p. 1831
Main Authors:	Nisthal, Alex, Hassanzadeh-Kiabi, Nargess, Avery, Kendra N., Rashid, Rumana, Diaz, Juan E., Muchhal, Umesh S., Chu, Seung Y., Moore, Gregory L., Bykova, Katrina, Desjarlais, John R.
Format:	Journal Article
Language:	English
Published:	01-07-2021
Online Access:	Get full text
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