Abstract 5373: In silico investigation of FOXM1 binding and novel inhibitors in epithelial ovarian cancer (EOC)

Objective: Using TCGA database, we had demonstrated that aberrantly activated Forkhead box M1 (FOXM1) correlates to worse overall survival in a subgroup of platinum resistant patients. Application of thiostrepton, a natural thiazole antibiotics that inhibits FOXM1 transcription activity, improves th...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 74; no. 19_Supplement; p. 5373
Main Authors:	Chen, Yi, Ruben, Eliza A., Bieber, Marcia M., Rajadas, Jayakumar, Teng, Nelson N.h
Format:	Journal Article
Language:	English
Published:	01-10-2014
Online Access:	Get full text
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