TMIC-33. MICROENVIRONMENT-DRIVEN CHANGES IN GLIOBLASTOMA CELL STATE SIGNATURES EXAMINED USING REGION-SPECIFIC HUMAN BRAIN ORGANOIDS

Cell state plasticity is retained by all stem-like and differentiated cells within glioblastoma (GBM) tumors. GBM cells can exploit these state-shifting capacities to evade and resist therapeutics. Thus, there is a need to identify and target the regulators of GBM cell state transitions. To address...

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Bibliographic Details

Published in:	Neuro-oncology (Charlottesville, Va.) Vol. 26; no. Supplement_8; p. viii305
Main Authors:	Bhatia, Tarun, Ganta, Saisrinidhi, Sing, Anson, King, Alexia, Sojka, Caitlin, Hoang, Kimberly, Nduom, Edjah, Read, Renee, Olson, Jeffrey, Sloan, Steven
Format:	Journal Article
Language:	English
Published:	11-11-2024
Online Access:	Get full text
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