Endothelial APP expression exacerbates cerebral amyloid angiopathy in AD model mice Development of new models and analysis methods/amyloid/Abeta

Abstract Background Most AD patients show accumulation of Ab peptides in both brain parenchyma and blood vessels. We recently found that brain vascular endothelial cells specifically express APP770 and produces Ab40/42. We then expect endothelial APP770 could contribute to cerebral amyloid angiopath...

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Bibliographic Details

Published in:	Alzheimer's & dementia Vol. 16; no. S2
Main Authors:	Tachida, Yuriko, Ogasawara, Naomi, Saito, Takashi, Shindo, Akihiro, Kawaguchi, Yasushi, Tomimoto, Hidekazu, Saido, Takaomi C., Kitazume, Shinobu
Format:	Journal Article
Language:	English
Published:	01-12-2020
Online Access:	Get full text
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