Criteria of primary screening of attenuated strains for live vaccine against Influenza A

Reassortant strains for live influenza vaccine (LIV) were selected using two additional markers: intensity of cytopathic effect (CPE) at 40 degrees C in MDCK cells and toxicity for mice (induction of acute hemorrhagic pulmonary edema after intranasal challenge with undiluted virus). All wild-type vi...

Full description

Bibliographic Details

Published in:	Voprosy virusologiĭ Vol. 45; no. 5; p. 22
Main Authors:	Kiseleva, I V, Naumenko, Z S, Kuznetsova, S A, Klimov, A I, Aleksandrova, G I
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-09-2000
Subjects:	Animals Influenza A virus - immunology Influenza A virus - isolation & purification Influenza A virus - pathogenicity Influenza Vaccines Mice Vaccines, Attenuated Virulence
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!