Exanthematous diseases and the first epidemic of dengue to occur in Manaus, Amazonas State, Brazil, during 1998-1999

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 37; no. 6; pp. 476 - 479
• Main Authors: De Figueiredo, Regina Maria Pinto, Thatcher, Bedsy Dutary, de Lima, Mário Lira, Almeida, Tânia Carvalho, Alecrim, Wilson Duarte, Guerra, Marcus Vinitius de Farias
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Medicina Tropical 01-11-2004
• Subjects: Adolescent; Adult; Aged; Antibodies, Viral - blood; Brazil - epidemiology; Child; Child, Preschool; Dengue - epidemiology; Dengue Virus - immunology; Disease Outbreaks; Enzyme-Linked Immunosorbent Assay; Exanthema - diagnosis; Exanthema - epidemiology; Exanthema - virology; Female; Humans; Immunoglobulin M - blood; Infant; Infant, Newborn; Male; Middle Aged; Rainforests; Seasons; Vector-borne diseases; Viral diseases; Brazil
• ISSN: 0037-8682; 1678-9849
• DOI: 10.1590/S0037-86822004000600009

In 1998, the FMT/IMT-AM foundation implemented the surveillance system to diagnose acute undifferentiated febrile syndromes, with the objective of active and passive surveillance in Brazilian western Amazonian rainforest to identify and diagnose the etiologic agents of acute fever. The diagnoses were performed using serological tests to detect IgM antibodies by ELISA (Enzyme-linked-immunosorbent assay) CDC/OPAS or using commercial kits. A total of 8,557 serum samples obtained from patients with clinical suspicion of dengue virus were analyzed. ELISA positive reaction to dengue virus was presented by 40% of the serum samples and 26% of the serum samples had positive ELISA reactions to other exanthematous viral diseases, such as rubella, measles, parvovirus, Oropouche virus and Mayaro virus.