CASE NOTE: Acute laryngotracheobronchitis and associated transient hyperphosphatasemia: A new case of transient hyperphosphatasemia in early childhood

CASE NOTE Acute laryngotracheobronchitis and associated transient hyperphosphatasemia: A new case of transient hyperphosphatasemia in early childhood

We report the case of a 20-month old boy with markedly elevated serum alkaline phosphatase (ALP) levels, documented during an episode of acute laryngotracheobronchitis. Biochemical investigations and imaging studies revealed no evidence of bone or liver disease. Transient hyperphosphatasemia (TH) wa...

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Bibliographic Details
Published in:Journal of paediatrics and child health Vol. 42; no. 3; pp. 149 - 150
Main Authors: Eboriadou, Maria, Skouli, Georgia, Panagopoulou, Paraskevi, Haidopoulou, Katerina, Makedou, Artemis, Varlamis, George
Format: Journal Article
Language:English
Published: Oxford Blackwell Publishing Ltd 01-03-2006
Subjects:
Biochemistry
Bronchitis
Case studies
Medical diagnosis
Pediatrics
Phosphates
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Summary:We report the case of a 20-month old boy with markedly elevated serum alkaline phosphatase (ALP) levels, documented during an episode of acute laryngotracheobronchitis. Biochemical investigations and imaging studies revealed no evidence of bone or liver disease. Transient hyperphosphatasemia (TH) was confirmed when serum ALP levels normalized within 2 months. Several theories were suggested for TH pathophysiology, viral infections among them; the exact causes, however, remain unclear. It is important to recognize TH and avoid misdiagnosis and unnecessary investigations.[PUBLICATION ABSTRACT]
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ISSN:1034-4810
1440-1754
DOI:10.1111/j.1440-1754.2006.00817.x