Efficacy and Tolerance of a Polymeric Surfactant Technology-Based Cleanser for Clinically Diagnosed Sensitive Skin

• Published in: Journal of drugs in dermatology Vol. 23; no. 10; p. 889
• Main Authors: Draelos, Zoe Diana, Hussain, Rabab, Smith, Heather, Shyr, Thomas, Tierney, Neena K
• Format: Journal Article
• Language: English
• Published: United States 01-10-2024
• Subjects: Adolescent; Adult; Aged; Cosmetics - administration & dosage; Cosmetics - adverse effects; Cosmetics - chemistry; Female; Gels; Humans; Male; Middle Aged; Polymers - administration & dosage; Polymers - chemistry; Skin Care - methods; Skin Diseases - diagnosis; Skin Diseases - drug therapy; Surface-Active Agents - administration & dosage; Surface-Active Agents - adverse effects; Surface-Active Agents - chemistry; Treatment Outcome; Young Adult
• ISSN: 1545-9616
• DOI: 10.36849/JDD.2024.8510

Cleansing is an important hygiene activity, necessary to prevent bacterial, fungal, yeast, and viral infection. However, in the presence of skin disease, cleansing can take on a new challenge: removing the sebum, sweat, externally applied substances, environmental debris, and organisms from the face without damaging the skin barrier. Since cleansers cannot easily distinguish between sebum and the intercellular lipids required to maintain skin integrity, unique cleansing technologies are necessary to provide mild cleansing for the many manifestations of sensitive skin.
This 4-week clinical study aimed to evaluate the appropriateness of a cosmetic facial foaming gel cleanser with a polymeric surfactant technology in a diverse sensitive skin population.
85 subjects with sensitive skin due to eczema/atopic dermatitis, rosacea, acne, or cosmetic intolerance syndrome were evaluated via investigator grading, self-assessment questionnaire, noninvasive measurements, and digital photography.
The foaming gel cleanser was well tolerated showing no significant increases in investigator-graded irritation endpoints. Sensitive skin subjects saw considerable reduction (P<0.05) in stinging, itching, burning, tightness, and overall sensitivity at 2 and 4 weeks. Improvements in smoothness, softness, clarity, radiance, and overall skin appearance, were observed by both the investigator and patients (P<0.05) at 2 and 4 weeks.
The polymeric surfactant technology-based foaming gel cleanser provided a rich, foaming lather that felt gentle and left skin feeling comfortable. J Drugs Dermatol. 2024;23(10):889-893. doi:10.36849/JDD.8510.