Erdheim-Chester disease detected with 99mTc MDP bone SPECT/CT

Erdheim-Chester disease (ECD) is a rare non-Langerhans' cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist.The les...

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Bibliographic Details
Published in:	JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR) Vol. 95; no. 4; p. 245
Main Authors:	Ceulemans, G, Keyaerts, M, Verbruggen, L, Hoorens, A, Boulet, C, Verdries, D, De Maeseneer, M, Ilsen, B, Everaert, H
Format:	Journal Article
Language:	English
Published:	Belgium 01-07-2012
Subjects:	Biopsy Bone and Bones - diagnostic imaging Bone and Bones - pathology Contrast Media Diagnosis, Differential Erdheim-Chester Disease - diagnostic imaging Erdheim-Chester Disease - pathology Female Gadolinium Humans Magnetic Resonance Imaging - methods Middle Aged Radiography Radiopharmaceuticals Technetium Tc 99m Medronate Tomography, Emission-Computed, Single-Photon - methods
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Summary:	Erdheim-Chester disease (ECD) is a rare non-Langerhans' cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist.The lesions consist of lipid-storing CD 68 +/CD 1a--non-Langerhans' cell histiocytes, most frequently localized in bone but also involving multiple organ systems in the body. We present a case report in which the diagnosis of ECD was established with 99mTc MDP bone SPECT/CT.
ISSN:	0302-7430