Study of the influence of low-dose γ-irradiation on the functional state of peripheral blood erythrocytes of rats

Low-intensity radiation at the absorbed dose of 4 μGy/min is a stressor of medium strength. In male Wistar rats, a pronounced and long-lasting response occurs in the system of red blood cells at the accumulated dose of 4.8 mGy. Functional deficiency of circulating cells was evaluated by the resistan...

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Bibliographic Details
Published in:	Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a Vol. 54; no. 5; p. 493
Main Authors:	Izmest'eva, O S, Luzianina, A A, Ershova, I L, Zhavoronkov, L P
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-09-2014
Subjects:	Animals Catalase - blood Catalase - radiation effects Erythrocytes - enzymology Erythrocytes - radiation effects Gamma Rays Male Radiation Dosage Rats Superoxide Dismutase - blood Superoxide Dismutase - radiation effects
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Summary:	Low-intensity radiation at the absorbed dose of 4 μGy/min is a stressor of medium strength. In male Wistar rats, a pronounced and long-lasting response occurs in the system of red blood cells at the accumulated dose of 4.8 mGy. Functional deficiency of circulating cells was evaluated by the resistance of erythrocytes to acid lyse and the activity of the main antioxidant enzymes--superoxide dismutase (SOD) and catalase (CAT). The minimum "threshold" doses of radiation that cause systemic reactions occur in the range of units of miligrey.
ISSN:	0869-8031