Rosai -Dorfman disease: a two cases report

• Published in: Tunisie Medicale Vol. 89; no. 5; p. 497
• Main Authors: Ben Turkia, Hadhami, Ben Romdhane, Manal, Azzouz, Hatem, Ben Chehida, Amel, Abdelmoula, Mohamed Slim, Ben Abdelaziz, Rim, Tebib, Neji, Ben Messoud, Monia, Sahtout, Samia, Chelly, Ines, Zitouni, Moncef, Mnif, Emna, Ben Dridi, Marie Francoise
• Format: Journal Article
• Language: French
• Published: Tunisia 01-05-2011
• Subjects: Child; Disease Progression; Histiocytosis, Sinus - complications; Histiocytosis, Sinus - diagnosis; Histiocytosis, Sinus - pathology; Histiocytosis, Sinus - therapy; Humans; Young Adult
• ISSN: 0041-4131

Rosai-Dorfman disease (RDD) is a benign lymphoproliferatif disorder characterized by cervical lymphadenopathies with a consistent risk of airways' compression and esthetical prejudice. Extra nodal localizations are also described.
To report two pediatric cases of RDD.
the first case concerned a patient with a prolonged nodal involvement of RDD. Remission seems to be natural although it coincided with a sulfaméthoxazole- triméthoprime therapy. The second case illustrated an extranodal form of RDD localized in soft tissue and paranasal sinus with extension to nasal cavity which were corticodependant.
RDD is usually a benign disorder. Particular localizations, lack of effective therapy and the high risk of recurrence are important issues in this rare affection.