Gastrointestinal stromal tumor: epidemiology and outcome study in 40 cases

• Published in: Tunisie Medicale Vol. 84; no. 1; p. 26
• Main Authors: Bellil, Khadija, Haouet, Slim, Bellil-Ben Haha, Selma, Jouini, Mohamed, Bouraoui, Saadia, Boubaker, Jalel, Boussen, Hamouda, Kchir, Nidhammeddine, Zitouna, Khaled
• Format: Journal Article
• Language: French
• Published: Tunisia 01-01-2006
• Subjects: Adult; Aged; Aged, 80 and over; Epidemiologic Studies; Female; Gastrointestinal Stromal Tumors - epidemiology; Gastrointestinal Stromal Tumors - pathology; Gastrointestinal Stromal Tumors - surgery; Humans; Incidence; Male; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis; Treatment Outcome
• ISSN: 0041-4131

The aim of this study was to analyze epidemiology and outcome of 40 patients with gastrointestinal stromal tumor (GIST) expressed CD 117. All epidemiological data (age, sex, location) and survival data were analyzed retrospectively. The tumors occurred in 17 men and 23 women. Stomach was the most common site of localization (47.5%). Of the 37 patients without Gleevec treatment, 18 benignant cases (66.6%) showed long-term survival (2 to 8 years) and 9 malignant cases (33.3%) were diagnosed. 10 cases were still being in followed (< 2 years). Gastric tumor's survival was better than extragastric tumor's survival without statistically significance (p>0.05). Our experience confirms that GIST is an aggressive tumor. 33.33% of them are malignant with recurrence or metastatic potential. Additionnally, epidemiologic factors (age, sex and location) do not have a predictive value.