Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome

Hereditary pancreatic carcinoma shows extant phenotypic and genotypic heterogeneity as evidenced by its integral association with a variety of hereditary cancer syndromes inclusive of the familial atypical multiple mole melanoma (FAMMM) syndrome in concert with CDKN2A (p16) germline mutations. Creig...

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Bibliographic Details
Published in:	Cancer Vol. 94; no. 1; pp. 84 - 96
Main Authors:	Lynch, Henry T, Brand, Randall E, Hogg, David, Deters, Carolyn A, Fusaro, Ramon M, Lynch, Jane F, Liu, Ling, Knezetic, Joseph, Lassam, Norman J, Goggins, Michael, Kern, Scott
Format:	Journal Article
Language:	English
Published:	United States 01-01-2002
Subjects:	Adult Age of Onset Aged Dysplastic Nevus Syndrome - genetics Dysplastic Nevus Syndrome - pathology Female Genes, p16 Germ-Line Mutation Humans Male Melanoma - genetics Melanoma - pathology Middle Aged Neoplastic Syndromes, Hereditary - classification Neoplastic Syndromes, Hereditary - genetics Neoplastic Syndromes, Hereditary - pathology Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Pedigree Phenotype Polymerase Chain Reaction Skin Neoplasms - genetics Skin Neoplasms - pathology
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