Evaluation of nasal inflammation

In the reaction of immediate hypersensibility to alergene is joined to its specific type IgE antibody, also united to the high affinity receptors for IgE (FccI) of the effecters cells fundamentally mastocites and basophiles. The interbreeding of these molecules Fcc to RI, after the union ofpolyvalen...

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Bibliographic Details
Published in:	Anales otorrinolaringologicos ibero-americanos Vol. 33; no. 2; p. 123
Main Authors:	De La Torre Morín, F, Sánchez Machín, I
Format:	Journal Article
Language:	Spanish
Published:	Spain 2006
Subjects:	Cytokines - metabolism Eosinophils - metabolism Humans Inflammation - metabolism Inflammation - pathology Mast Cells - pathology Nasal Cavity - metabolism Nasal Cavity - pathology Phospholipids - metabolism Receptors, Histamine H2 - metabolism
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Summary:	In the reaction of immediate hypersensibility to alergene is joined to its specific type IgE antibody, also united to the high affinity receptors for IgE (FccI) of the effecters cells fundamentally mastocites and basophiles. The interbreeding of these molecules Fcc to RI, after the union ofpolyvalent antigenes to IgE, active these cells, producing three biologic responses: excitosis of the preformed content of its granules, synthesization of lipidic mediators and citoquine secretion. The inflammation mediators are in last term, substances responsible of the clinic symptomatology. They can be divided generally in preformed mediators (biogene amines and macromolecules of the granules) and of new synthese mediators (lipidic and citoquine mediators).
ISSN:	0303-8874