Clinical, biochemical, and morphological characteristics of chronic hepatitis with various etiology

To investigate clinicomorphological features in patients with chronic diffuse lesions of the liver with consideration of the etiological factor. Clinical, laboratory, serological and pathohistological examinations were performed in 67 patients with chronic hepatitis (CH). Out of 48 patients with chr...

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Bibliographic Details
Published in:	Terapevtic̆eskii arhiv Vol. 74; no. 2; p. 35
Main Authors:	Masevich, Ts G, Ermolaeva, L G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2002
Subjects:	Adolescent Adult Alanine Transaminase - blood Alcoholism - complications Aspartate Aminotransferases - blood Bilirubin - blood Fatty Liver - etiology Female Hepatitis, Chronic - diagnosis Hepatitis, Chronic - etiology Hepatitis, Chronic - pathology Hepatitis, Viral, Human - complications Hepatitis, Viral, Human - diagnosis Hepatitis, Viral, Human - pathology Humans Liver Cirrhosis - etiology Male Middle Aged Substance-Related Disorders - complications
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Summary:	To investigate clinicomorphological features in patients with chronic diffuse lesions of the liver with consideration of the etiological factor. Clinical, laboratory, serological and pathohistological examinations were performed in 67 patients with chronic hepatitis (CH). Out of 48 patients with chronic viral hepatitis (CVH), 32(66.6%) demonstrated association of hepatic lesion with alcohol or drug abuse. Knodell activity in the liver was prevalent in drug abusers with CVH. Fat dystrophy and high de Ritis index were typical for alcoholics. Viral hepatic lesions associated neither with alcohol nor drug abuse occur only in 1/3 of patients with CH.
ISSN:	0040-3660