Total intravenous anesthesia with propofol, fentanyl and clopheline in young children with occlusive hydrocephalus during ventriculoperitoneal shunting

• Published in: Anesteziologiia i reanimatologiia no. 6; p. 52
• Main Authors: Shefer, S P, Pelogeevskaia, Z I, Liapin, A P, Savvina, I A, Portniagin, I V, Zaĭtseva, N V, Kuz'menko, I G
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01-11-1999
• Subjects: Age Factors; Analgesics - administration & dosage; Analgesics - pharmacology; Anesthesia, Intravenous; Anesthetics, Intravenous - administration & dosage; Anesthetics, Intravenous - pharmacology; Body Weight; Cerebrovascular Circulation - drug effects; Clonidine - administration & dosage; Clonidine - pharmacology; Fentanyl - administration & dosage; Fentanyl - pharmacology; Hemodynamics - drug effects; Humans; Hydrocephalus - surgery; Infant; Infant, Newborn; Propofol - administration & dosage; Propofol - pharmacology; Time Factors
• ISSN: 0201-7563

Total intravenous anesthesia with propofol, fentanyl, and clonidine was used in infants aged under 1 year operated on for occlusive hydrocephalus. The course of anesthesia in 18 patients with the hypertensive hydrocephalus syndrome is analyzed. Four of these patients with an extremely grave premorbid history and body weight of 1-3 kg were operated on before the age of 2 months. Propofol can be used in infants aged under 1 year, including physiologically immature small-for-date infants. Clonidine, an alpha 2-adrenoagonist, used in older neurosurgical patients and adults for stabilizing cerebral perfusion pressure, is allowed in infants, too. The authors analyze the time course of central hemodynamics during anesthesia with propofol, fentanyl, and clonidine and anesthesia by other drugs (combined anesthesia with ketamine and opioid analgesics, neuroleptanalgesia).